Mechanisms, assessment and therapeutic implications of lung hyperinflation in COPD
نویسندگان
چکیده
منابع مشابه
Longitudinal changes in lung hyperinflation in COPD
PURPOSE COPD is characterized by an accelerated and progressive decline in forced expiratory volume in 1 second (FEV1) and lung hyperinflation. Although lung hyperinflation is the hallmark of COPD, data on the longitudinal changes in lung hyperinflation and any association with the decline in FEV1 are lacking. The aim of this study was to evaluate the longitudinal changes in lung hyperinflation...
متن کاملPhysiology and consequences of lung hyperinflation in COPD
Lung hyperinflation commonly accompanies expiratory flow limitation in patients with chronic obstructive pulmonary disease (COPD) and contributes importantly to morbidity and an impoverished quality of life. It is not surprising, therefore, that lung hyperinflation has become an important therapeutic target in symptomatic COPD patients. Acute dynamic increases in lung hyperinflation under condi...
متن کاملLung hyperinflation in COPD: the impact of pharmacotherapy
Improvement in airway function in response to bronchodilator therapy is generally confirmed by simple spirometry. However, improvements in maximal expiratory flow rates have been shown to correlate poorly with important patient-centred outcomes, such as reduced exertional dyspnoea and improved exercise performance. Recent studies have suggested that attendant reductions in end-expiratory lung v...
متن کاملCPAP decreases lung hyperinflation in patients with stable COPD.
BACKGROUND Dynamic hyperinflation, caused by expiratory flow limitation, markedly increases resting end-expiratory lung volume (functional residual capacity) in many COPD patients. OBJECTIVE To determine the impact and duration of impact of CPAP on hyperinflation and airway resistance in patients with stable COPD. METHODS In a case series, 21 patients underwent CPAP at 8 cm H(2)O for 15 min...
متن کاملLUNG HYPERINFLATION IN COPD: What the Clinician Needs to Know
Lung hyperinflation, chronic dyspnea and reduced exercise capacity are inextricably linked and are independent predictors of increased mortality in COPD. It is no surprise, therefore, that a major goal of management is to reduce lung hyperinflation in the hope of improving dyspnea, exercise tolerance and related long term patientcentered outcomes. The negative effects of lung hyperinflation on ...
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ژورنال
عنوان ژورنال: Respiratory Medicine
سال: 2015
ISSN: 0954-6111
DOI: 10.1016/j.rmed.2015.03.010